How To
RE2: All lock and safe combos

- February 8, 2019
- Updated: July 2, 2025 at 5:24 AM

Resident Evil 2 is just as much of a puzzle game as it is a survival horror game. As you fight for your survival against the zombie hordes, you’re bound to come up against some locked safes and doors that contain all sorts of useful supplies. The solutions and combos, however, aren’t easy to find. If you’re hurting for supplies and don’t have time to hunt down those elusive codes, check out our guide to find out how to open all the locks and safes in the game.
RE2: All lock and safe combos
Waiting Room Safe

Location: Waiting Room (second floor, east wing)
Combo: Left 6, Right 2, Left 12- this combo can be found in the Confiscation Report document.
Contents: Matilda muzzle break (Leon), JMB Hp3 high capacity mag (Claire)
The Complete Resident Evil 2 Survival Guide
Read Now ►Men’s Locker Room Locker

Location: Men’s Locker Room (second floor, west wing)
Combo: CAP- written on a whiteboard in the Operations Room storage area
Contents: Shotgun Shells (Leon), Flame Rounds (Claire)
3F Hallway Locker

Location: Northwestern staircase, top floor
Combo: DCM- obtained via a film roll
Contents: Magnum Ammo (Leon), Submachine Gun Ammo (Claire)
RE2: How to survive the Tyrant
Read Now ►West Office Safe

Location: West Office, first floor
Combo: Left 9, Right 15, Left 7- found in the S.T.A.R.S. Office Memo
Contents: Hip Pouch (both characters)
Leon’s Desk Puzzle

Location: West Office, first floor
Combo: NED (left lock), MRG (right lock)- found by inputting first initials of all officer’s names for each side of the room
Contents: Matilda High Capacity Mag (Leon), SLS-60 Speed Loader (Claire)
RE2: All weapons and how to find them
Read Now ►Control Room Locker

Location: Control Room, sewer area
Combo: SZM- found via circled letters in Jazz Festival Flyer
Contents: Magnum Ammo (Leon), Submachine Gun Ammo (Claire)
RE2: The 4th Survivor guide
Read Now ►Treatment Pool Safe

Location: Treatment Pool Room, sewer area
Combo: Left 2, Right 12, Left 8- written on the side of the safe in chalk
Contents: W-870 Shotgun Stock (Leon), SLS-60 Reinforced Frame (Claire)
Alex's first experience with video games came at the tender young age of 12, when his parents gave him and his brothers a PlayStation 2 for Christmas. They’ve probably been regretting that mistake ever since, because as soon he finished his first lap in Gran Turismo 3, Alex was hooked for life. In addition to writing for Softonic, Alex has turned that love of games into a voice acting career, and has voiced everything from grizzled old soldiers to vampire lords. When he's not gaming or getting behind the microphone, Alex can probably be found wandering the woods around Boston or putting together some new culinary delight in his kitchen.
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